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Is Lexapro a type of benzo?

Written by Brandon Okey. Mina Draskovic, B.Psy., reviewed this content for accuracy.

Lexapro (escitalopram) and benzodiazepines are different medications, though some people confuse them. Both treat anxiety but through distinct mechanisms with different risk profiles. Benzos include medications such as Valium and Xanax. They target your brain’s GABA system for immediate anxiety relief, while Lexapro works through an entirely different pathway that builds up over weeks. 

Benzos work quickly but can be habit-forming. Lexapro takes time but offers long-term stability without the same dependency issues.

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Anxiety and depression often occur alongside other challenges, which is why our dual diagnosis treatment addresses your mental health and any substance concerns simultaneously. We create personalized care plans that go beyond medication, helping you develop sustainable strategies for lasting wellness and recovery.

What drug class is Lexapro?

Lexapro belongs to a class of medications known as selective serotonin reuptake inhibitors (SSRIs). This type of antidepressant increases levels of serotonin in the brain, a neurotransmitter that helps regulate mood, anxiety, and emotional well-being. 

As an SSRI, Lexapro is the first-line treatment for depression and anxiety disorders because of its effectiveness and relatively manageable side effect profile. It’s primarily prescribed to treat:

  • Major depression.
  • Generalized anxiety disorder.
  • Panic disorder.
  • Social anxiety disorder.
  • Obsessive-compulsive disorder (OCD).
  • Post-traumatic stress disorder (PTSD).

Unlike some other psychiatric medications, Lexapro doesn’t work immediately. Most patients require daily doses for several weeks before experiencing full therapeutic benefits. During this time, your healthcare professional will monitor your symptoms and may adjust your dosage based on your treatment response.

Lexapro is available as a brand-name or generic drug, with dosing typically ranging from 10–20 mg daily for most adults. Your healthcare provider will determine the appropriate dose based on your specific symptoms, medical conditions, and other factors unique to your situation.

Differences between Lexapro and benzodiazepines

Lexapro and benzodiazepines treat anxiety through different mechanisms in the brain. They produce distinct effects, timelines, and risk profiles.

  • Lexapro works by balancing serotonin levels to improve mood and anxiety over several weeks. Benzodiazepines provide quick relief by enhancing GABA activity in the brain, often working within 30–60 minutes.
  • Benzodiazepines pose serious risks when combined with alcohol or opioids because they may cause potentially dangerous respiratory depression. Lexapro has its own interaction concerns, particularly with other serotonergic drugs or monoamine oxidase inhibitors, which can increase the risk of serotonin syndrome (a rare but serious condition).
  • For long-term treatment of psychiatric disorders, like generalized anxiety and depression, healthcare providers prefer Lexapro because of its better safety profile for extended use. Benzodiazepines are typically reserved for short-term treatment or breakthrough panic attacks rather than daily, ongoing therapy.
  • The side effect profiles differ significantly. Lexapro’s common side effects include gastrointestinal issues, sexual dysfunction, and mild sedative effects. Benzodiazepines more commonly cause pronounced sedation, coordination problems, and memory issues. 
  • Benzodiazepines carry a high risk of physical dependence and withdrawal symptoms when stopped, unlike Lexapro which typically causes milder withdrawal effects.

Healthcare providers now recommend a combined approach for severe anxiety. Gomez, et. al. propose short-term benzodiazepines for immediate relief during the 4–8 weeks while Lexapro gradually reaches its full effectiveness. This strategy maximizes the strengths of both medications while minimizing the long-term dependency risks associated with benzodiazepines.

Many people who start taking benzodiazepines for legitimate reasons find themselves physically dependent within just a few weeks. If you want to break free from benzo dependence, you will need more than willpower. Our benzodiazepine detox program provides 24/7 medical supervision throughout the withdrawal process, gradually tapering your dosage. Through comprehensive therapy, we address the underlying anxiety that led to medication use in the first place.

Is Lexapro stronger than Xanax?

Lexapro and Xanax aren’t directly comparable because they use different action mechanisms. Xanax provides rapid relief by enhancing GABA activity, typically working within 15–30 minutes, which makes it more immediately potent for acute anxiety episodes and panic attacks. Lexapro gradually increases serotonin levels over 2–4 weeks and offers more subtle but sustained relief for depression and anxiety conditions.

For someone experiencing a panic attack, Xanax might feel “stronger” momentarily. If you’re looking to manage anxiety long-term, Lexapro is more effective with fewer risks of dependency and cognitive impairment. Elderly patients generally tolerate Lexapro better, and it causes less pronounced sedation than Xanax.

Research shows benzodiazepines are slightly more effective at treating anxiety symptoms than SSRIs such as Lexapro. A 2018 meta-analysis demonstrated that benzos had a 50% greater statistical effect on anxiety reduction than SSRIs, though this difference must be weighed against their higher dependency risks.

We understand the trap of Xanax dependence and offer a carefully designed path to freedom. Our medical team provides 24/7 monitoring during the detox phase, gradually reducing your dosage to minimize withdrawal symptoms. Beyond addiction treatment, our mental health services include cognitive behavioral therapy, mindfulness training, and trauma-focused counseling to help you develop lasting emotional resilience and coping strategies.

Reach out to Ardu today and transform your relationship with anxiety without relying on benzodiazepines.

Is Lexapro addictive?

Lexapro is not considered addictive in the way that benzodiazepines are. SSRI antidepressant medications don’t produce euphoria, cravings, or drug-seeking behavior typically associated with addiction. 

Patients taking Lexapro for extended periods may experience withdrawal symptoms if they stop the medication abruptly. Lexapro withdrawal signs may include:

  • Dizziness and lightheadedness.
  • Nausea or upset stomach.
  • Headaches.
  • “Brain zaps” (sensations of electrical shock in the head).
  • Irritability or mood swings.
  • Anxiety or increased nervousness.
  • Fatigue or unusual tiredness.
  • Insomnia or vivid dreams.
  • Confusion or difficulty concentrating.
  • Flu-like symptoms (muscle aches, chills).
  • Sensory disturbances (tingling, numbness).
  • Vertigo or balance problems.

These withdrawal effects are different from addiction and reflect the body’s physiological adjustment to changing serotonin levels. To avoid them, healthcare professionals recommend gradually tapering off Lexapro under medical supervision so the brain can adjust slowly to decreasing levels of the medication.

There’s a distinction between physical dependence and addiction: your body may become accustomed to having Lexapro (dependence), but you generally won’t develop compulsive drug-seeking behavior or lose control over your use (addiction). Most patients take Lexapro as prescribed for depression symptoms or anxiety disorders without misuse.

Reach out to our anxiety and depression treatment center

Mental health treatment requires expert care, personalized approaches, and comprehensive support that addresses symptoms and underlying causes. Our specialized mental health treatment program provides evidence-based care for those struggling with anxiety, depression, and medication management challenges. 

Managing anxiety and depression often requires more than medication. We provide the comprehensive care, education, and support needed for lasting recovery and improved quality of life. Whether you’re dealing with side effects from Lexapro or are concerned about benzodiazepine dependence, our team is here to help.

We offer:

  • Comprehensive medication evaluation: Our medical professionals carefully assess your current medications to make sure you’re on the optimal treatment plan.
  • Dual diagnosis treatment: Many people with anxiety or depression struggle with substance use issues. Our integrated approach addresses both conditions simultaneously.
  • Evidence-based therapy options: From cognitive behavioral therapy (CBT) to dialectical behavior therapy (DBT), we provide proven therapeutic approaches that complement medication management.
  • Personalized wellness planning: We help you develop sustainable coping strategies beyond medication, incorporating nutrition, exercise, mindfulness, and stress management techniques.
  • Supportive transition care: Our team assists with medication adjustments, tapering plans, and long-term strategies to maintain your mental health improvements.

If you or a loved one is struggling with anxiety, depression, or questions about medication management, our compassionate team is ready to help. Call us at (801) 872-8480 to learn more about our treatment options and take the first step toward better mental health.

Brandon Okey

Brandon Okey is the co-founder of Ardu Recovery Center and is dedicated to empowering people on their journey to sobriety.

Is Lexapro a benzo FAQ

Does Lexapro contain benzos?

Lexapro contains no benzodiazepines. These are different prescription medications with distinct active ingredients and mechanisms. Lexapro belongs to the selective serotonin reuptake inhibitor class used primarily for treating depression and anxiety disorders. 

Unlike benzos, which produce immediate effects by enhancing GABA activity, Lexapro gradually regulates serotonin levels over weeks.

Is Lexapro an upper or downer?

Lexapro doesn’t fit into “upper” or “downer” categories that typically describe stimulants or depressants. As an SSRI antidepressant medication, it works by balancing brain chemistry rather than artificially stimulating or sedating your central nervous system. Patients with depressive disorders often report improved energy levels and reduced lethargy over time, while those with anxiety symptoms typically experience a calming effect without significant sedation. 

Some people initially notice mild sedative effects, particularly when first starting treatment or increasing their dose of escitalopram. These temporary side effects generally resolve as your body adjusts to the medication’s therapeutic action on serotonin levels.

Is Lexapro an opioid?

Lexapro is not an opioid. It belongs to the selective serotonin reuptake inhibitor (SSRI) class of antidepressant drugs used to treat depression symptoms and anxiety disorders. Opioids target pain receptors, while Lexapro regulates serotonin levels to improve mood and reduce anxiety. 

Unlike opioids, Lexapro doesn’t produce the euphoria, respiratory depression, or high addiction potential that characterizes opioid medications. Lexapro carries different risk profiles and potential adverse effects than opioid drugs. People with mental health conditions such as depressive disorder or generalized anxiety typically benefit from SSRIs without the dependency concerns associated with opioid treatment.

Is 40 mg of Lexapro high?

40 mg of Lexapro exceeds standard therapeutic recommendations. Medical advice generally indicates that doses above 20 mg daily offer minimal additional benefit while substantially increasing risks of adverse effects including gastrointestinal bleeding, sexual dysfunction, and potential serotonin syndrome. The typical adult dosage ranges from 10–20 mg for treating depressive disorders and anxiety symptoms. 

Healthcare professionals might occasionally prescribe higher doses for treatment-resistant conditions, but this requires careful monitoring of vital signs and potential drug interactions. If you’re taking more than the recommended dose of escitalopram, consult your licensed healthcare professional immediately about appropriate adjustments to your medication schedule.

Why is Lexapro called the happy pill?

Lexapro earned the nickname “happy pill” because it treats depressive symptoms by normalizing serotonin levels in the brain, helping restore emotional balance for people with depression and anxiety disorders. Unlike substances that produce artificial euphoria, Lexapro works gradually over several weeks to alleviate signs of depression, like persistent sadness, withdrawal from friends, and loss of interest in activities. Healthcare professionals generally avoid this oversimplified terminology because it doesn’t accurately reflect how SSRIs work.

How sedating is Lexapro?

Lexapro produces mild sedative effects in approximately 10–15% of patients, significantly less than benzodiazepines or tricyclic antidepressants. These effects typically manifest as drowsiness or fatigue, particularly during the initial weeks of treatment. Most people find that sedation diminishes as their body adjusts to the medication. For those with insomnia or anxiety symptoms, this mild sedation can be beneficial, especially when the dose of escitalopram is taken in the evening. 

Patients with depression may sometimes experience the opposite effect: increased energy and reduced lethargy as their depressive symptoms improve. If sedation becomes problematic, consult your healthcare provider about adjusting your medication schedule.

What cannot be taken with Lexapro?

Several medication combinations with Lexapro can cause dangerous drug interactions. 

  • Never combine it with monoamine oxidase inhibitors (MAOIs) because this risks potentially fatal serotonin syndrome with symptoms including muscle rigidity, confusion, and elevated vital signs. 
  • Other serotonergic drugs, including tricyclic antidepressants and certain pain medications, can also increase serotonin to dangerous levels. 
  • Nonsteroidal anti-inflammatory drugs (NSAIDs) may increase risks of gastrointestinal bleeding when taken regularly with Lexapro. 
  • Alcohol can worsen depressive symptoms and side effects. 
  • Some migraine medications and certain psychiatric treatments can create problematic interactions affecting heart rhythm. 

Always provide your complete list of prescription medications to your healthcare professional before starting any new treatment.

What is the best time to take Lexapro for anxiety?

For treating anxiety symptoms, the timing for Lexapro depends on your response and daily routine. Many healthcare professionals recommend morning administration for patients who experience activation or energy improvement, while evening dosing works better for those who notice sedative effects. 

Some patients report that morning dosing helps manage daytime symptoms of anxiety while minimizing sleep disturbances. Others find that taking Lexapro before bedtime reduces adverse effects like nausea or headaches by sleeping through the initial response.

Resources

Gomez AF, Barthel AL, Hofmann SG. Comparing the efficacy of benzodiazepines and serotonergic anti-depressants for adults with generalized anxiety disorder: a meta-analytic review. Expert Opin Pharmacother. 2018 Jun;19(8):883-894. doi: 10.1080/14656566.2018.1472767. Epub 2018 May 28. PMID: 29806492; PMCID: PMC6097846.

Further reading

OTC meds that test positive for benzos

Using benzos for alcohol withdrawal

Is Adderall a type of benzodiazepine drug?

How does alcohol affect your mental health?

10 warning signs of addiction

How do benzos affect sleep?

How long do benzos stay in your system?

Benzodiazepine toxicity