Written by Brandon Okey. Mina Draskovic, B.Psy., reviewed this content for accuracy.
For many, grabbing a beer or glass of wine after work is a favorite way to unwind and relax. But what happens when one drink turns into several on a regular basis?
More importantly, what kind of long-term effects can alcohol have on your brain?
While an occasional drink may not cause concern, heavy drinking can take a major toll on our overall health, including our liver, kidneys, behavior, and brain. Research shows that excessive alcohol consumption actually damages areas of the brain vital for functions like learning, memory, motor skills, and emotional regulation.
If you are struggling with alcohol abuse, our alcohol addiction treatment program in Utah can help you find your way back to vitality.
Alcohol adversely affects the brain. It impacts both structure and function: it induces structural changes in the brain while also interfering with its intricate chemical signaling.
Some of these effects are acute—they go away when your body gets rid of its toxins—while others can be long-lasting. The end result may be physical and functional brain damage that can undermine a person’s cognitive abilities, emotional state, and self-control.
Let’s dig deeper into the ways alcohol affects your brain.
While alcohol impacts nearly every brain cell, there are parts of our brain that seem particularly vulnerable to alcohol’s damaging effects. These include:
The frontal lobe plays a key role in executive functioning. It controls your judgment, planning, problem-solving, and impulse control. When this part of your brain is heavily influenced or damaged, you often experience increased impulsivity and find it hard to regulate your behavior.
The effects of alcohol on frontal lobe activity, even in the short term, can cloud your judgment and reduce inhibitions. You become more impulsive, engage in atypical behaviors (e.g., inappropriate speech, aggression, risky sexual encounters, or dangerous risk-taking), and are less able to consider the consequences of your actions.
Sound familiar? Here comes the scary part.
A 2022 study found that “alcohol intake is negatively associated with global brain volume measures, regional gray matter volumes, and white matter microstructure.” In other words, your brain can actually shrink in volume due to heavy drinking.
Your brain does physically shrink as you get older, but heavy alcohol consumption can make this shrinkage worse. According to research, “light to moderate alcohol consumption did not increase the rate of frontal lobe shrinkage, whereas heavy drinkers had significantly shrunken frontal lobes compared with abstainers.”
Brain shrinkage can damage neurons and affect important neurotransmitters. This is medically known as cerebral atrophy. It can make chronic alcoholics lose up to a sixth of their total brain mass. Cerebral atrophy impacts both gray and white matter in areas involved in cognition, motor skills, and emotion regulation.
Did you ever wonder why you get so clumsy after a few too many drinks? That’s your cerebellum calling it quits. This brain region tucked right under your brain’s rear lobe is key for fluid movements and good coordination.
Booze causes cerebellar dysfunction and ataxia (problems with coordination), seen in alcoholics and even in children with fetal alcohol spectrum disorder. The reasons for this are not entirely clear, but it seems that alcohol disrupts communication between brain cells and damages structures within the cerebellum. Neurons can’t seamlessly do their job, causing signals to misfire between your brain and your muscles.
Excessive alcohol exposure results in cerebellar ataxia and alterations in hand movements, speed when striking a target, impaired postural stability and balance, and slower attenuated foot taping. In addition, the developing cerebellum is particularly vulnerable to the toxic effects of alcohol. (Luo)
Here’s how alcohol prevents your cerebellum from doing its job:
This is exactly why you shouldn’t drink and drive.
The hippocampus is essential for learning new information and forming memories. This seahorse-shaped region consolidates short-term memories into long-term storage so they can be retrieved later. Damage to the hippocampus causes severe short- and long-term memory impairments.
When alcohol inhibits hippocampus activity, even in the short term, it hinders the brain’s ability to solidify new information and experiences into memory. This causes the classic experience of an alcohol-induced blackout, where you cannot recall events that occurred while you were chugging heavily.
People with alcohol-damaged hippocampus may frequently repeat themselves, forget appointments or obligations, and struggle with learning. That’s because heavy drinking decreases the size of the hippocampus.
Individuals with heavier drinking patterns had a larger rate hippo-parahippocampal volume decline. This higher rate of GMV decline in the hippocampus was associated with poorer memory, and with greater number of memory blackouts. (Meda, et. al.)
Heavy drinkers often struggle with learning new information, but prospective memory also suffers. That’s your ability to remember future plans and obligations. While failing to remember you have lunch with your in-laws this coming Thursday isn’t so bad, the negative effects of alcohol on your hippocampus over time can lead to much more serious consequences.
The hypothalamus is a small brain structure that acts as the control center for many important bodily processes and behaviors. Among other things, it regulates body temperature, hunger, sex drive, and emotional responses through the autonomic nervous system.
Heavy drinking suppresses hypothalamic activity and disrupts normal signaling between the hypothalamus and pituitary gland (which produces chemical messengers called neurotransmitters).
Here’s what happens when your hypothalamus is intoxicated:
Alcohol use disorder often decreases the levels of thiamine (vitamin B21). Thiamine is an essential nutrient for brain health that helps produce energy from sugars and supports proper neuron function. Alcohol decreases thiamine absorption, leading to a severe deficiency over time. This condition is known as Wernicke-Korsakoff Syndrome.
A major consequence of severe thiamine deficiency is damage to regions of the brain like the hypothalamus.
…thiamine deficiency may result in damage to portions of the hypothalamus (perhaps because blood vessels break in that region). According to this hypothesis, alcoholics who are susceptible to alcohol toxicity may develop permanent or transient cognitive deficits associated with brain shrinkage. (Oscar-Berman & Marinkovic)
Oscar-Berman and Marinkovic also suggest that people “susceptible to thiamine deficiency will develop a mild or transient amnesic disorder, with short-term memory loss as the salient feature.”
If you recognize any of these symptoms of alcohol misuse in yourself, now might be a good time for a change. In our alcohol rehab center, you’ll find skilled professionals ready to help you every step of the way toward building a healthier, happier life in recovery.
Alcohol directly affects the function of neurotransmitters. Neurotransmitters are chemical messengers that allow neurons to send signals (messages) to each other. They play distinct roles in cognition, movement, mood, reward, and other brain functions.
According to research, alcohol hijacks the brain’s reward and stress pathways by altering neurotransmitter activity, which drives addictive behaviors that can eventually lead to alcoholism.
Alcohol interacts with several neurotransmitter systems in the brain’s reward and stress circuits. These interactions result in alcohol’s acute reinforcing effects. Following chronic exposure, these interactions in turn cause changes in neuronal function that underlie the development of alcoholism.
Excessive drinking alters levels of GABA, glutamate, dopamine, serotonin, and acetylcholine, which leads to communication disruptions between neurons. Here are their key functions:
The way alcohol interferes with neurotransmitter activity can disrupt vital processes like learning, memory, motor control, pleasure, and mood regulation. Imbalances in these chemical messengers underlie many of alcohol’s effects on thinking, emotions, and behavior.
Over time, increased tolerance, addiction, and alcohol withdrawal symptoms all boil down to the way alcohol messes with your brain’s chemistry.
We’ve established how booze hijacks the brain’s reward and stress circuits by directly mucking with neurotransmitters. It throws off the delicate balance between chemicals that end up exciting the brain more than they calm it down. When your brain experiences pleasure and happiness while intoxicated, why should it give that up?
That’s how your tolerance to larger amounts of alcohol increases until addiction develops.
…physical dependence, which refers to the pharmacological tolerance induced by chronic alcohol intake, results in AWS and is neurobiologically supported by the imbalance between GABA and glutamate-NMDA neurotransmission. (Banerjee)
Let’s break this down a bit.
Banerjee also explains how these neurotransmitters “have been implicated in alcohol addiction due to their imbalance in the brain, which could be either due to their excess activity or inhibition.”
…what begins as a mild way to seek pleasure, soon turns into a full-fledged addiction as the alcohol begins to cause widespread neuroadaptations in the brain, causing the person to convert from an alcohol non-addict to an alcohol addict. Such changes in the reinforcing value of alcohol during the transition from alcohol use to dependence reflect adaptive neural changes resulting from chronic exposure to high alcohol quantities.
Our inpatient program helps you overcome your alcohol addiction and withdrawal symptoms. Here at Ardu, you will learn healthy coping strategies to deal with alcohol cravings. After completing the inpatient portion, you can continue on the road to recovery with our intensive outpatient program.
Reach out and change your life for the better.
I hold the experience I had at Ardu very close to my heart and stringing some words together won’t ever be able to adequately describe what it did for my life. Which is save it. Ultimately, I know it was me who made the decision to change, but without the guiding hand, compassion, challenges, and honest work from the therapist and staff, I wouldn’t be where I am today.
— Lani Lye
Chronic alcohol misuse has negative effects on your memory. As the hippocampus and frontal lobes get bogged down by alcohol, concentration and memory start to stutter. Your thinking becomes muddled, slow, and disjointed.
These combined effects on memory circuits lead to the so-called “brain fog” often reported by heavy drinkers. Brain fog is a fancy name for mental confusion, decreased clarity of thought, and an inability to focus properly. People with alcohol-related brain fog describe feeling mentally sluggish, slow, and fuzzy.
What’s behind the brain drain?
For one, alcohol directly suppresses glutamate. Oscar-Berman and Marinkovic show that even a small amount of alcohol interferes with this key excitatory chemical, making it harder for the brain to form memories. Hence those pesky blackouts drinkers experience.
Small amounts of alcohol have been shown to interfere with glutamate action. This interference could affect several brain functions, including memory, and it may account for the short-lived condition referred to as “alcoholic blackout.”
During alcohol withdrawal, these excessive glutamate receptors become overactive, potentially causing cell death and brain damage manifesting as seizures or strokes.
To make things worse, alcohol also drains acetylcholine levels, another neurotransmitter vital for memory consolidation and learning. Running low on acetylcholine, you struggle to focus, recall facts, or memorize new stuff.
While alcohol may provide temporary relief or euphoria, the truth is that it inflicts lasting damage to your brain when consumed heavily over the years. It’s not just bad hangovers and foggy mornings at stake—we’re talking long-term cognitive decline, increased dementia risk, permanent motor problems, strained relationships, and the threat of addiction.
Chronic alcohol use may:
If you or someone you know is struggling with alcohol dependence, our team of experts is here to provide support, guidance, and compassionate care as you take the important steps toward recovery. Don’t wait until the damage becomes irreversible.
Chronic and heavy alcohol consumption can lead to permanent damage to the brain. Based on everything we know about the effects of alcohol on the brain, here’s what you need to know about how dangerous excessive alcohol consumption is:
Do you want to stop drinking? Our residential treatment health care team can help you get sober and maintain your sobriety.
Brain damage from alcohol is a complex issue, and it’s not always easy to pinpoint. That’s because alcohol affects individuals differently depending on factors like genetics, the amount consumed, and the duration of use.
There is no single definitive indicator that alcohol has damaged the brain. Alcohol-related neurological damage manifests in subtle, nonspecific ways that emerge gradually over time. Rather than distinct symptoms, what typically appear first are vague symptoms like mild cognitive difficulties and emotional changes.
That being said, there are some general indicators that binge drinking may impact your brain:
Remember, it’s never too late to make positive changes in your life. Seeking help is a crucial first step toward addressing any potential brain damage from alcohol.
Contact Ardu Recovery Center and learn how to take care of your brain’s health.
Structural changes in the brain, such as a decrease in brain volume, are hard to fully reverse. However, our brain has the ability to recover and regenerate, and, in some cases, brain damage caused by binge drinking may be reversed.
The extent of recovery depends on factors like:
There is some potential to reverse brain damage, but full recovery from alcohol is very difficult to achieve. Here’s how you can help your brain regain some of its health and function:
It is extremely challenging to repair the damage inflicted by years of heavy alcohol abuse, but there are dedicated recovery programs that can help regain some cognitive abilities. Our alcohol detox center offers individualized care to free yourself from the grip of alcohol addiction and help your brain on the path to healing and renewed vitality.
Learn more about the six stages of alcohol recovery that can help you overcome alcohol addiction and live a happier, healthier life.
Alcohol-related brain damage is difficult to recover from, but not impossible. At our addiction recovery center, we specialize in helping people like you break free from the grip of alcohol addiction. Our team of skilled and experienced addiction specialists is here to provide the support, guidance, and personalized treatment you need to embark on your journey to recovery.
The recovery process begins with alcohol detox, where we safely and comfortably help you rid your body of alcohol toxins. Our medical professionals at our detox center closely monitor your progress to ensure a smooth and safe detox experience. Detox is an essential first step, allowing your body to cleanse and heal from the harmful effects of alcohol consumption.
We believe in a comprehensive approach to recovery, so we tend to address not only the physical aspects but also the psychological and emotional aspects of addiction. We offer group therapy and individual therapy to all our patients, as well as holistic treatment methods that delve into the underlying factors contributing to your alcohol addiction.
Remember, you don’t have to face this alone. We are here to support you every step of the way. If you’re ready to take the first step toward a healthier, alcohol-free life, reach out to us today.
Brandon Okey is the co-founder of Ardu Recovery Center and is dedicated to empowering people on their journey to sobriety.
Alcohol can have particularly detrimental effects on the developing brains of individuals under the age of 21. The brain continues to undergo significant changes and growth during adolescence and early adulthood. Alcohol interferes with this process, potentially causing lasting damage.
Alcohol impairs the development of the prefrontal cortex, the part of the brain responsible for decision-making, impulse control, and judgment. This can lead to risky behaviors, poor decision-making, and impulsivity, which are more pronounced in young people.
Also, the hippocampus, vital for memory formation, can be negatively affected by alcohol. Memory and learning deficits may result from heavy drinking during adolescence.
Research suggests that young people who start drinking before age 15 are more likely to develop alcohol dependence later in life, indicating that early exposure to alcohol can increase the risk of long-term addiction.
The brain has some capacity for recovery from the effects of alcohol, but full recovery may be difficult, especially in cases of chronic and heavy alcohol abuse. Some brain functions can improve with abstinence. For example, cognitive abilities such as attention, memory, and problem-solving may partially recover. The brain’s plasticity allows it to adapt and repair itself to some extent.
However, in cases of severe alcohol use disorder or long-term heavy drinking, certain brain damage may be irreversible. Conditions like Wernicke-Korsakoff Syndrome, which results from thiamine deficiency due to alcoholism, can lead to permanent brain damage.
Heavy drinking is typically defined as excessive alcohol consumption that exceeds recommended guidelines and poses significant health risks.
For men, consuming more than 4 alcoholic drinks in a day or more than 14 drinks per week is considered excessive. For women, excessive drinking involves consuming more than 3 drinks in a day or more than 7 drinks per week.
Memory impairment while drinking is a common phenomenon. Alcohol affects the brain in several ways that contribute to memory loss:
The severity of memory impairment can vary based on factors such as the amount of alcohol consumed, individual tolerance, and genetic predisposition. Excessive drinking can lead to more pronounced memory problems and pose long-term risks to cognitive function.
Chronic alcohol abuse can lead to permanent damage in various parts of the brain, including:
The extent of brain damage varies depending on the duration and severity of alcohol abuse. While some recovery is possible with abstinence and treatment, certain impairments may be irreversible.
Daviet, R., Aydogan, G., Jagannathan, K., Spilka, N., Koellinger, P. D., Kranzler, H. R., Nave, G., & Wetherill, R. R. (2022). Associations between alcohol consumption and gray and white matter volumes in the UK Biobank. Nature Communications, 13(1), 1-11. https://doi.org/10.1038/s41467-022-28735-5
Kubota M, Nakazaki S, Hirai S, et al. Alcohol consumption and frontal lobe shrinkage: study of 1432 non-alcoholic subjects. Journal of Neurology, Neurosurgery & Psychiatry 2001;71:104-106
Luo, J. (2015). Effects of ethanol on the cerebellum: Advances and prospects. Cerebellum (London, England), 14(4), 383. https://doi.org/10.1007/s12311-015-0674-8
Meda, S. A., Hawkins, K. A., Dager, A. D., Tennen, H., Khadka, S., Austad, C. S., Wood, R. M., Raskin, S., Fallahi, C. R., & Pearlson, G. D. (2018). Longitudinal effects of alcohol consumption on the hippocampus and parahippocampus in college students. Biological Psychiatry. Cognitive Neuroscience and Neuroimaging, 3(7), 610. https://doi.org/10.1016/j.bpsc.2018.02.006
Oscar-Berman, M., & Marinkovic, K. (2003). Alcoholism and the Brain: An Overview. Alcohol Research & Health, 27(2), 125-133. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668884/
Banerjee, N. (2014). Neurotransmitters in alcoholism: A review of neurobiological and genetic studies. Indian Journal of Human Genetics, 20(1), 20-31. https://doi.org/10.4103/0971-6866.132750
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